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RESEARCH                                                                 

 

HIGHER DEGREE

 

Doctor of Philosophy

The Effects of SMA-Pirarubicin as a Selective Tumour Targeting Agent for the Treatment of Colorectal Cancer Liver metastases, PhD, University of Melbourne, 2011

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Honours

Effect of Thalidomide on Colorectal Cancer Liver Metastases, BBiomed Sci Honours, University of Melbourne 2004

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Research Associate - VERITAS - Victorian Collaborative for Education, Research, Innovation, Training and Audit by Surgical Trainees

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INTERNATIONAL MULTICENTRE COLLABORATIVES 

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PUBLICATIONS

First Author

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1.     Daruwalla J, Sachithanandan N, Andrews D & Miller, J. Ectopic intravagal parathyroid adenoma. Head and Neck, 37(12):200-

        204, 2015.

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2.     Daruwalla J, Malcontenti Wilson, Muralidharan V & Christophi C. Styrene maleic acid copolymer–pirarubicin induces tumor-

        selective oxidative stress and decreases tumor hypoxia as possible treatment of colorectal cancer liver metastases. Surgery,

        158(1):236-247, 2015.

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3.     Daruwalla J, Murray D, Pande G, An unusual case of small bowel obstrcution. ANZJS, 85(5):391-392, 2015

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4.     Daruwalla J, Hadge A, Wen S & Nikfarjam M. High fat diet is not associated with stimulation of colorectal cancer liver

        metastases. World Journal of Surgical Research. 3:38, 2014.

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5.     Daruwalla J, Maddern G. The effect of fatigue on simulated laparoscopic surgical skills: a comparative historical control

        cohort study. ANZ Journal of Surgery. 84:137–142, 2014.

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6.     Daruwalla J, Malcontenti Wilson, Muralidharan V, Maeda H & Christophi C. In vitro and in vivo evaluation of tumor targeting 

        SMA- pirarubicin micelles: Survival improvement and inhibition of liver metastases. Cancer Science. 101(8):1866-1874,

        2010. Figure 7 used - Front Cover of issue (see background).

     

7.     Daruwalla J, Greish K, Malcontenti-Wilson C, Muralidharan V, Iyer A, Maeda H, Christophi C. Styrene maleic acid-pirarubicin

        disrupts tumor microcirculation and enhances the permeability of colorectal liver metastases. Journal of Vascular                          Research. 46 (3): 218-228, 2009.

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8.     Daruwalla J, Greish K, Malcontenti-Wilson C, Muralidharan V, Maeda H & Christophi C. SMA-pirarubicin induces tumor                    selective oxidative damage and reduces tumor hypoxia. Annals of Oncology. 18 (VII34-VII34), 2007.

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9.     Daruwalla J, Nikfarjam M, Greish K, Malcontenti Wilson, Maeda H & Christophi C. Evaluation of the effect of SMA-pirarubicin

        micelles on colorectal cancer liver metastases and of hyperbaric oxygen in CBA mice. Journal of Drug Targeting. 15(7-8):

        487- 495, 2007.

 

10.   Daruwalla J, Malcontenti Wilson, Maeda H & Christophi C. Hyperbaric oxygen therapy for malignancy: A review. World

         Journal of Surgery. 30(12): 2112-2131, 2006.

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11.   Daruwalla J and Christophi C. The effect of hyperbaric oxygen therapy on tumour growth in a mouse model of colorectal

        cancer liver metastases. European Journal of Cancer. 42(18): 3304-3311, 2006

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12.   Daruwalla J, Greish K, Nikfarjam M, Malcontenti-Wilson C, Maeda H & Christophi C. SMA-pirarubicin inhibits growth of                     colorectal cancer liver metastases in an animal model. Cancer Research. 66 (8): 721, 2006.

 

13.   Daruwalla J, Nikfarham M, Malcontenti Wilson, Fanartzis M & Christophi C. Effect of thalidomide on colorectal liver

        metastases. Journal of Surgical Oncology. 91(2): 134-140, 2005.

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Co-Authored
 

1.    Determination of “borderline resectable” pancreatic cancer – a global assessment of 30 shades of grey. HPB, Manuscript               Number: HPB-D-23-00043R1 (Submitted June 2023)

 

2.    COVIDSurg3 Collaborative. Reducing the environmental impact of surgery on a global scale: systematic review and co-                   prioritization with healthcare workers in 132 countries. British Journal of Surgery, Volume 110, Issue 7, Pages 804–817, July           2023.  â€‹

 

3.    POSTVenTT Collaborative. The management of peri-operative anaemia in patients undergoing major abdominal surgery in         Australia and New Zealand: a prospective cohort study. Medical Journal of Australia, 217(9):487-493. doi:                                          10.5694/mja2.51725, Novemeber 2022.

 

4.   Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index                  across 1632 hospitals in 119 countries. Lancet, 5;400(10363):1607-1617. doi: 10.1016/S0140-6736(22)01846-3. November              2022.

 

5.   COVIDSurg Collaborative*. SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective          cohort study. Anaesthesia, doi: 10.1111/anae.15563, August 2021.

 

6.    COVIDSurg Collaborative*. Resilience of elective cancer surgery systems during COVID-19 lockdowns: International,                       prospective cohort study of planned surgery for 15 tumour types in 61 countries Annals of Oncology, 33 (5), August 2021.

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7.    COVIDSurg Collaborative and GlobalSurg Collaborative. SARS-CoV-2 vaccination modelling for safe surgery to save lives:               data from an international prospective cohort study. British Journal of Surgery, March 2021.

       Authorship: https://biblio.ugent.be/publication/8699263/file/8699266.docx

 

8.     COVIDSurg Collaborative and GlobalSurg Collaborative. Timing of surgery following SARS-CoV-2 infection an international            prospective cohort study. Anaesthesia, March 2021.

        Authorship: https://biblio.ugent.be/publication/8699263/file/8699266.docx

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9.     Gao N, Guest G, Thomson BN, Bozin M, Mann B, Tan S, Clark DA, Daruwalla J, et al., Laparoscopic or open appendicectomy

        for suspected appendicitis in pregnancy, evaluation of fetal outcome in Australia. ANZJS. Sept 6 Epub 2016

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10.   Fifis T, Nguyen L, Malcontenti Wilson, Chan L, Costa P, Daruwalla J, Nikfarjam M, Muralidharan V, Waltham M, Thompson E            & Christophi C. Treatment with the vascular disruptive agent OXi4503 induces an immediate and widespread Epithelial to

        Mesenchymal Transition (EMT) in the surviving tumor, Cancer Medicine. 2(5): 595-610 2013

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11.  Satasivam P, Lim M, Reeves F, Daruwalla J, Casan J, Lim C & Royce P. The effect of oral anticoagulation on the incidence and

       management of haematuria in a contemporary Australian patient cohort. British Journal of Urology International.

       110(Suppl 4): 80-84, 2012

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12.  Maeda H, Bharate G, & Daruwalla J. Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect.

       European Journal of Pharmacy and Biopharmacy. 71(3): 409-419, 2009

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13.  Chan LS, Daruwalla J & Christophi C. Selective targeting of the tumour vasculature. ANZ Journal of Surgery. 78(11): 955-967,

        2008

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14.   Fifis T, Lam I, Malcontenti-Wilson C, Daruwalla J, Chan L, Harun N, Christophi C & Loveland B. Immunization with Heat-                  Stressed Tumour Cells Reduces Colorectal Cancer Liver Metastases. Tissue Antigens. 66 (5): 416-417, 2005.

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15.  Nikfarjam M, Malcontenti-Wilson C, Fanartzis M, Daruwalla J, & Christophi C. A model of partial hepatectomy in mice.

        Journal of Investigative Surgery. 17(5): 291-294, 2004.

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